EZI-DOCK - Ezi-Flow™ CSV All Plastic MK5

RX Code: ECA

High-Containment, Fully Disposable Containment Powder Transfer system for Pharmaceutical Manufacturing

The Ezi-Flow™ CSV MK5 All Plastic is the next generation of Ezi-Dock’s fully disposable, high-containment powder transfer systems. Designed for sterile and potent API handling, the MK5 combines the proven OEB 5 / <1.0 μg/m³ OEL containment performance of the MK5 with a series of engineering enhancements that improve operator safety, ease of use, and process efficiency.

Its single-use design eliminates cleaning validation and cross-contamination risk, supporting faster changeovers, reduced downtime, and more reliable production workflows. The MK5’s upgraded active unit, quick-release spigot, and refined passive interface deliver smoother operation, stronger connections, and improved ergonomics. Lightweight, liquid-tight full-bore connections and compatibility with gamma irradiation or autoclave sterilisation make it ideal for aseptic and GMP-compliant manufacturing.

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Side view of disassembled Ezi-Flow CSV MK5 for single-use for high-containment powder transfer
Reactor charging Facilitates the safe and controlled transfer of powders into reactors for pharmaceutical processing.
Dispensing Enables precise and contamination-free dispensing of APIs and other powdered substances.
Blending Ensures homogeneous mixing of powders while preventing cross-contamination.
Dry granulation Supports high-containment granulation processes to maintain material integrity.
Tablet press charging Provides a safe and efficient transfer of granulated powders into tablet presses.
Powder filling lines Allows seamless, contained powder transfer for automated filling operations.
  • High Containment (<1.0 µg/m³ OEL)
    Fully enclosed transfer with improved seals and locking mechanisms for maximum operator protection.
  • Single-Use Simplicity
    No cleaning or validation required, reducing downtime and contamination risk.
  • Enhanced Ergonomics & Handling
    Compact pleated bellows, larger toggles, and quick-release spigot design make changeovers faster and easier.
  • Improved Process Safety
    Replaceable collar and seal reduce particle generation and exposure risk during maintenance.
  • Optimised Connection Security
    Bayonet-style, rotational locking interface delivers a stronger, more reliable active-to-passive connection.
  • cGMP & Sterile Compatibility
    Gamma or autoclave sterilisation ready for aseptic processes.
  • Material Versatility
    Available in polypropylene (standard), PTFE, or PEEK for enhanced chemical and thermal resistance.
  • Connection Sizes: 4-inch and 6-inch full-bore
  • Containment Level: <1.0 µg/m³ OEL (OEB 5)
  • Sealing System: Liquid-tight, closed-transfer design
  • Material Options:
    • Polypropylene (standard)
    • PTFE or PEEK (optional for high-performance needs)
  • Sterilisation Compatibility: Gamma irradiation or autoclave

A Cost-Effective, Single-Use Alternative to Traditional SBVs

Traditional stainless steel split butterfly valves (SBVs) from providers such as ChargePoint and Andocksysteme can be costly, complex, and cleaning-intensive. The CSV MK5 All Plastic offers a simpler and more flexible solution. It integrates seamlessly into isolators, cleanrooms, and closed-transfer systems, providing the same containment performance without the burden of maintenance or cleaning validation.

Available in polypropylene (standard), PTFE, or PEEK for enhanced chemical and thermal resistance, the MK5 system is suitable for a wide range of pharmaceutical applications, including reactor charging, dispensing, blending, and tablet press charging. It enables manufacturers to meet strict regulatory standards while lowering total cost of ownership.

Side view of disassembled Ezi-Flow CSV MK5 for single-use for high-containment powder transfer
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Interested in improving your containment material transfer with Ezi-dock’s Single-Use Ezi-FlowTM CSV All Plastic System? Request a free, no-obligation quote, ask questions, or schedule a demo. Feel free to get in touch with us!

Phone:  +31 85 043 3110
Email: info@romynox.nl

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